# Software Engineer, Staff: Applied AI, Science & Engineering at Anthropic

- Company: Anthropic
- What the company does: Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems. Backed by Accel, Bessemer and General Catalyst.
- Company website: https://www.anthropic.com/
- Type: Startups (AI role)
- Level: Senior
- Location: New York City, NY; San Francisco, CA; Seattle, WA
- Work setup: On-site
- Posted: 2026-10-06
- Apply by: 2026-11-20
- Apply: https://job-boards.greenhouse.io/anthropic/jobs/5444766008?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/anthropic-software-engineer-staff-applied-ai-science-and-engineering/

## About the role

At Anthropic, we're building AI systems that are safe, beneficial, and transformative. Our mission is to develop AI that benefits humanity, and we believe the most powerful capabilities emerge when we thoughtfully bridge the gap between research breakthroughs and real-world applications. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Build the agent harnesses and research loops that let Claude carry a problem from literature review through hypothesis generation, simulation, analysis, and design iteration
- Connect scientific computing and simulation tools (finite element, CFD, electromagnetic, or molecular modeling codes, for example) so Claude can drive them reliably and at scale
- Design and build evaluations that tell us whether Claude's work is actually right, and be honest about where it isn't
- Sit with scientists and engineers at partner organizations to learn their problem, data, tools, and constraints, and turn open-ended questions into well-specified, verifiable tasks with clear success criteria
- Prototype with partners, ship pilots into their workflows, and cut anything that doesn't move the problem forward
- Turn what works in one engagement into shared tools, reusable components, and documented processes the next one can start from

Tags: Engineering & Design - Product

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/anthropic-software-engineer-staff-applied-ai-science-and-engineering/