# Director, DMPK (or Senior Director) at BioAge Labs

- Company: BioAge Labs
- What the company does: BioAge Labs (BIOA) is finding new ways to treat disease by targeting the mechanisms of aging, with the ultimate goal of increasing healthy human lifespan. https://bioagelabs.com. Backed by a16z, Pear VC and Felicis.
- Company website: https://bioagelabs.com
- Type: Startups
- Level: Principal and up
- Location: Remote (United States)
- Work setup: Remote
- Pay: $230K to $290K base salary per year (USD)
- Posted: 2026-08-13
- Apply by: 2026-10-08
- Apply: https://ats.rippling.com/bioage-labs/jobs/87b569af-4ce6-4dd4-9f7c-86d7194249fa
- Page: https://www.1752.vc/careers/jobs/bioage-labs-director-dmpk-or-senior-director/

## About the role

Reporting to the VP, Non Clinical Development, the Director, DMPK will lead the company's DMPK and translational pharmacology function, collaborating across disciplines to optimize candidate selection, clinical translation, and regulatory success.

## What they're looking for

- Lead the Drug Metabolism and Pharmacokinetics (DMPK) and translational pharmacology strategy across BioAge's pipeline, supporting programs from lead optimization through IND-enabling studies and clinical development
- Design, oversee, and interpret in vitro and in vivo DMPK, ADME, metabolite identification, and bioanalytical studies to enable informed candidate selection and progression decisions
- Partner closely with Medicinal Chemistry, Discovery Biology, Biomarkers, Toxicology, Clinical Pharmacology, and Clinical Development to integrate DMPK data into overall program strategy and decision-making
- Provide scientific leadership for first-in-human dose projections, clinical pharmacology strategy, and translational plans that bridge preclinical findings to clinical development
- Identify and proactively address DMPK risks and optimization opportunities, including drug-drug interaction potential, metabolite characterization, formulation considerations, and species translation
- Select, manage, and oversee external CROs and strategic partners conducting DMPK, bioanalytical, and translational pharmacology studies, ensuring high scientific quality, timely execution, and regulatory compliance

Tags: R&D