# (Associate) Director, Clinical Science at Centessa Pharmaceuticals

- Company: Centessa Pharmaceuticals
- What the company does: Patient-Centric Mission. Asset-Centric Approach. We’re pursuing our Orexin Receptor 2 Agonist Program to bring potentially transformative treatment options to patients with sleep-wake, neurological, neurodegenerative and neuropsychiatric disorders.... Backed by Foresite Capital.
- Company website: https://centessa.com
- Type: Startups
- Level: Principal and up
- Location: Boston, MA
- Work setup: On-site
- Posted: 2026-09-21
- Apply by: 2026-11-05
- Apply: https://job-boards.greenhouse.io/centessapharmaceuticalsinc/jobs/6202566004?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-associate-director-clinical-science/

## About the role

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Advanced scientific/clinical degree (PhD or PharmD) required
- 8-10 years of experience in clinical research or clinical development within the biotechnology or pharmaceutical industry
- Deep understanding of clinical trial design, clinical data analysis, and drug development principles, with direct experience leading or supporting early-phase (Phase 1/2) clinical trials
- Demonstrated ability to independently lead complex scientific workstreams and influence cross-functional teams in a fast-paced biotech environment
- Proven experience leading the development and authorship of clinical and regulatory documents (e.g., protocols, IBs, CSRs, briefing documents)
- Strong analytical and scientific interpretation skills, including the ability to synthesize emerging clinical, safety, and biomarker data into actionable insights

Tags: Clinical Development

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-associate-director-clinical-science/