# Senior Advisor, Molecular Pharmacology at Centessa Pharmaceuticals

- Company: Centessa Pharmaceuticals
- What the company does: Patient-Centric Mission. Asset-Centric Approach. We’re pursuing our Orexin Receptor 2 Agonist Program to bring potentially transformative treatment options to patients with sleep-wake, neurological, neurodegenerative and neuropsychiatric disorders.... Backed by Foresite Capital.
- Company website: https://centessa.com
- Type: Startups
- Level: Senior
- Location: Boston, MA
- Work setup: On-site
- Posted: 2026-09-10
- Apply by: 2026-10-25
- Apply: https://job-boards.greenhouse.io/centessapharmaceuticalsinc/jobs/6188561004?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-senior-advisor-molecular-pharmacology/

## About the role

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- PhD in Pharmacology, Neuroscience, or a closely related scientific discipline with substantial experience in supporting drug discovery research
- Minimum of 5 years of relevant industry experience
- Strong foundation in molecular pharmacology, with expertise in one or more areas such as receptor pharmacology, GPCR biology, cellular signaling, mechanistic pharmacology, neuroscience, or related disciplines
- Broad understanding of experimental approaches used to characterize compound pharmacology, receptor and target biology, and biological mechanisms
- Experience developing scientific strategy and independently addressing complex experimental and drug discovery questions
- Demonstrated ability to integrate data across experimental systems and scientific disciplines

Tags: Discovery Operations

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-senior-advisor-molecular-pharmacology/
