# Senior Director, Global Medical Affairs at Centessa Pharmaceuticals

- Company: Centessa Pharmaceuticals
- What the company does: Patient-Centric Mission. Asset-Centric Approach. We’re pursuing our Orexin Receptor 2 Agonist Program to bring potentially transformative treatment options to patients with sleep-wake, neurological, neurodegenerative and neuropsychiatric disorders.... Backed by Foresite Capital.
- Company website: https://centessa.com
- Type: Startups
- Level: Principal and up
- Location: Boston, MA
- Work setup: On-site
- Posted: 2026-09-09
- Apply by: 2026-10-24
- Apply: https://job-boards.greenhouse.io/centessapharmaceuticalsinc/jobs/6185815004?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-senior-director-global-medical-affairs/

## About the role

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Advanced scientific or clinical degree (MD, PharmD, or PhD)
- Minimum 10 years of Medical Affairs leadership experience with 5 years global experience preferred
- Experience in neuroscience, sleep medicine, neurology, psychiatry, or rare disease
- Demonstrated experience leading at least one successful global product launch (North America, Europe, and Asia-Pacific markets highly preferred)
- Experience serving as a global medical lead for late-stage development or commercial products
- Strong understanding of global medical affairs, evidence generation, payer evidence requirements, and commercialization readiness

Tags: Medical Affairs

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/centessa-pharmaceuticals-senior-director-global-medical-affairs/