# Scientist II, Scaling Lead at Evolutionary Scale

- Company: Evolutionary Scale
- What the company does: ESM3. Enabling scientists to understand, imagine, and create proteins. Backed by Lux.
- Company website: https://evolutionaryscale.ai
- Type: Startups (AI role)
- Level: Senior
- Location: San Francisco, CA (Onsite)
- Work setup: On-site
- Pay: $138K to $172K base salary per year (USD)
- Posted: 2026-08-27
- Apply by: 2026-10-11
- Apply: https://job-boards.greenhouse.io/biohub/jobs/8122754
- Page: https://www.1752.vc/careers/jobs/evolutionary-scale-scientist-ii-scaling-lead/

## About the role

Biohub is seeking a Scientist II to lead the scaling of our imaging and data-generation pipeline. This role will set throughput targets, find the bottlenecks that matter most, and work hands-on with the sample-prep, imaging, and computation teams to remove them — at the bench, at the microscope, and at the keyboard.

## What they're looking for

- Improve multi-specimen acquisition, instrument uptime, and cross-instrument reproducibility on the group's light-sheet microscopes, pushing sustained throughput toward the platform's practical limits
- Establish reproducible SOPs, QC gates, and monitoring to ensure improvements persist as the team, instruments, and datasets scale — and to measure throughput, not assume it
- Serve as the connective tissue between the group and Biohub's shared platforms, removing cross-team bottlenecks and helping the group hit its shared throughput milestones
- Mentor and technically guide team members, translate scaling strategy into concrete engineering and experimental plans, and help recruit as the effort grows
- Document architectures, protocols, release methods, code, and data for the community, in keeping with Biohub's open-science ethos

Tags: R&D