# Senior / Principal Data Infrastructure Engineer at Flagship Pioneering

- Company: Flagship Pioneering
- What the company does: Pioneering Partnerships Latest News.
- Company website: https://www.flagshippioneering.com
- Type: VC firms
- Level: Principal and up
- Location: Cambridge, MA USA
- Work setup: On-site
- Pay: $165K to $209K base salary per year (USD)
- Posted: 2026-10-08
- Apply by: 2026-11-22
- Apply: https://boards.greenhouse.io/flagshippioneeringinc/jobs/8869701002?gh_jid=8869701002&utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/flagship-pioneering-senior-principal-data-infrastructure-engineer/

## About the role

We are seeking a highly skilled, hands-on Senior / Principal Data Infrastructure Engineer to design, build, and own the data systems that make our proteomics data discoverable, trustworthy, and usable across the organization. Expedition Medicines develops machine learning tools trained on proteomics data generated by our experimental platform, and this role is critical to the robust, scalable collection, management, and analysis of that data at scale. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Bachelor's degree in Computer Science, Data Engineering, Computational Biology, Proteomics, or a related technical field, advanced degree is a plus
- 8+ years of hands-on experience in data infrastructure, data engineering, informatics, or related fields, preferably in proteomics, bioinformatics, or other biotech environments
- Proven track record of independently designing, building, and operating terabyte-scale data systems in a biotech or life sciences environment
- Demonstrated ability to set technical direction and deliver complex projects with minimal oversight
- Expertise in cloud infrastructure (e.g., AWS, Azure), Kubernetes, and infrastructure management as code tools (CFN, CDK, Terraform, ARM)
- Experience with data pipeline architecture and workflow orchestration (e.g., Flyte, Dagster, Airflow), including APIs, schedulers, and software integration

Tags: Computational & Data Sciences

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/flagship-pioneering-senior-principal-data-infrastructure-engineer/