# Principal Business Manager, Early Clinical Development (ECD) at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups
- Level: Principal and up
- Location: South San Francisco
- Work setup: On-site
- Pay: $136K to $253K base salary per year (USD)
- Posted: 2026-10-01
- Apply by: 2026-11-15
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Principal-Business-Manager--Early-Clinical-Development--ECD-_202610-125004-1?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/genentech-principal-business-manager-early-clinical-development-ecd/

## About the role

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD. Reporting directly to the ECD Chief of Staff, this role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight, and execution across the department. This position requires SSF on-campus presence between 3 to 4 times a week based on business demands. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Education & Certifications: Bachelor’s degree required, project management or process improvement certifications (PMP, Six Sigma, Agile, Change Management) preferred
- Experience: 5–10 years in business management, cross-functional initiatives, or operations programs (clinical development experience preferred)
- Core Competencies: Expertise in strategic planning, project management, business process improvement, and team facilitation
- Problem Solving & Innovation: Proactive problem solver skilled at challenging standard processes, proposing creative solutions, and adapting to fast-changing demands
- Communication & Relationships: Strong written, oral, and presentation skills with a proven ability to build transparent, productive cross-functional relationships
- Change Leadership: Demonstrated ability to develop and execute change management and communication strategies across the enterprise


Source: 1752vc Careers, https://www.1752.vc/careers/jobs/genentech-principal-business-manager-early-clinical-development-ecd/