# Scientist 3/4, Complex in Vitro Systems at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups
- Level: Mid level
- Location: South San Francisco
- Work setup: On-site
- Pay: $100K to $186K base salary per year (USD)
- Posted: 2026-10-14
- Apply by: 2026-11-28
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Scientist-3-4--Complex-in-Vitro-Systems_202610-125661?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/genentech-scientist-3-4-complex-in-vitro-systems/

## About the role

In this lab-based role, you will provide scientific and technical expertise in stem cell culture, induced pluripotent stem cell (iPSC)-derived systems, 3D cell and tissue models, and complex in vitro platforms. Responsibilities include culturing and characterizing advanced cellular models, designing and executing model development and qualification studies, establishing functional and phenotypic assays, analyzing and interpreting complex datasets, and maintaining rigorous, high-quality documentation. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Maintain and expand human stem cell and iPSC cultures, including differentiation, maturation, cryopreservation, quality control, and phenotypic characterization
- Design and execute experiments to establish the reproducibility, robustness, and biological relevance of complex in vitro models
- Develop and apply functional and phenotypic assays using approaches such as cytotoxicity and viability assays, immunofluorescence, confocal and high-content imaging, molecular profiling, and functional readouts
- Support the development and application of ocular complex in vitro models, including retinal, RPE, vascular, organoid, and co-culture systems, to address drug discovery and translational questions
- Apply rigorous experimental design, troubleshooting, and protocol optimization to establish reproducible and scalable workflows
- Analyze and interpret multidimensional datasets and clearly communicate findings, limitations, and recommendations to collaborators and stakeholders


Source: 1752vc Careers, https://www.1752.vc/careers/jobs/genentech-scientist-3-4-complex-in-vitro-systems/