# Senior Physical AI & Robotics Scientist - Lab Automation at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups (AI role)
- Level: Senior
- Location: South San Francisco
- Work setup: On-site
- Pay: $168K to $312K base salary per year (USD)
- Posted: 2026-10-13
- Apply by: 2026-11-27
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Senior-Physical-AI---Robotics-Scientist---Lab-Automation_202610-125975?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/genentech-senior-physical-ai-and-robotics-scientist-lab-automation/

## About the role

The expected salary range for this position based on the primary location of San Francisco is $168,100 - 312,300 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Apply system identification, domain randomization, and sim-to-real tuning to ensure simulation-trained control policies execute predictably on physical hardware
- Fine-tune multimodal Vision AI models (VLMs, NVIDIA Cosmos) using synthetic failure datasets (Isaac Sim) for real-time detection of lab anomaly modes (spills, bubbles, dropped microplates, tilted lids, tip-pick misses)
- Optimize low-latency inference with TensorRT on NVIDIA Jetson (Thor/Orin) edge hardware, combining visual servoing and closed-loop feedback control so systems self-correct without halting master workflows
- Harness OpenUSD scene graphs to represent workcell geometry and state, integrating synchronization services to link executable digital twins across heterogeneous hardware APIs (SiLA 2, gRPC, vendor SDKs)
- Strong interest in translating physical AI capabilities into biological workflows and drug discovery pipelines
- Passionate builder with a proven track record of taking real-world robotic manipulation and sim-to-real systems beyond demonstrations into sustained operation


Source: 1752vc Careers, https://www.1752.vc/careers/jobs/genentech-senior-physical-ai-and-robotics-scientist-lab-automation/