# Senior/Principal Scientist, Computational Neuroscience, Computational Sciences Center of Excellence at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups
- Level: Principal and up
- Location: South San Francisco
- Work setup: On-site
- Pay: $145K to $269K base salary per year (USD)
- Posted: 2026-09-01
- Apply by: 2026-10-16
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Senior-Principal-Scientist--Computational-Neuroscience--Computational-Sciences-Center-of-Excellence_202607-119869
- Page: https://www.1752.vc/careers/jobs/genentech-senior-principal-scientist-computational-neuroscience-computational-sc/

## About the role

Working within and extending Roche’s existing data ecosystems to accelerate our Neuroscience portfolio. Developing strategy to effectively mine large data and drive science using LLMs, advanced automation and AI agents.

## What they're looking for

- The ideal candidate will have deep experience in many of the following types of analysis:
- Perturb-seq and related CRISPR screening
- Patient tissue or CSF/PBMC atlases
- Use of human genetics to prioritize drug targets
- Familiarity with AI approaches and AI agents to enable scientific insights
- A track record of impactful scientific achievement, which may be demonstrated by co-first/lead as well as contributing author publications