# Senior Principal Statistician, Early Development (Director Level) at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups
- Level: Principal and up
- Location: South San Francisco
- Work setup: On-site
- Pay: $172K to $319K base salary per year (USD)
- Posted: 2026-09-11
- Apply by: 2026-10-26
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Senior-Principal-Statistician--Early-Development_202605-111191
- Page: https://www.1752.vc/careers/jobs/genentech-senior-principal-statistician-early-development-director-level/

## About the role

The Early Development Senior Prinicpal Statistician is a critical partner in the design and analysis of exploratory clinical studies, applying statistical expertise to guide early-phase trial strategy, design, and interpretation. This role ensures scientific rigor while maintaining the flexibility needed for hypothesis generation and signal detection.

## What they're looking for

- You hold a PhD or MSc in Statistics, Biostatistics, or a closely related quantitative field
- You bring a minimum of 12 years of experience in clinical trial statistics, including advanced contributions to early development strategy
- You have recognized expertise in applying advanced statistical design and modeling approaches (e.g., Bayesian adaptive trials, model-based decision-making) in early phase clinical development
- You have a proven record of leadership in high impact cross functional projects or initiatives across multiple molecules or disease areas
- You have outstanding communication skills with the ability to influence senior clinical and regulatory stakeholders
- You demonstrate independent thinking and make decisions based on sound principles