# Senior Scientist, Biochemical and Cellular Pharmacology at Genentech

- Company: Genentech
- What the company does: Genentech discovers, develops, manufactures and commercializes treatments for patients with serious and life-threatening medical conditions. Backed by North Carolina Biotechnology Center.
- Company website: https://gene.com
- Type: Startups
- Level: Senior
- Location: South San Francisco
- Work setup: On-site
- Posted: 2026-09-11
- Apply by: 2026-10-26
- Apply: https://roche.wd3.myworkdayjobs.com/en-US/ROG-A2O-GENE/job/South-San-Francisco/Senior-Scientist--Biochemical-and-Cellular-Pharmacology_202608-122218
- Page: https://www.1752.vc/careers/jobs/genentech-senior-scientist-biochemical-and-cellular-pharmacology/

## About the role

Provide Strategic Leadership: Serve as the primary GPCR expert and strategic advocate for Biochemical and Cellular Pharmacology on multidisciplinary project teams, contributing both at the bench and at leadership levels to drive decision-making. Drive Pharmacological Characterization: Oversee and contribute to rigorous in vitro pharmacological characterization to advance lead candidates in the cardiovascular, renal, or metabolic disease fields.

## What they're looking for

- Ph.D. in Pharmacology, Biochemistry, Cell Biology, or a related scientific discipline with 1–5 years of postdoctoral and/or industry experience
- Demonstrated expertise in receptor theory, signal transduction pathways, allosteric modulation, and biased signaling, along with hands-on experience across diverse GPCR assay platforms (e.g., cAMP, calcium flux, BRET/FRET, Beta-arrestin recruitment)
- Expertise in cardiovascular, renal, or metabolic disease fields
- Passionate about dissecting complex receptor pharmacology and translating its functional impact into disease-relevant biological readouts using advanced model systems
- Experience working with a wide range of primary cells and gene-editing techniques (e.g., CRISPR)
- Proven track record in developing, optimizing, and troubleshooting biochemical and cell-based assay cascades in primary and recombinant systems