# Senior / Executive Director of Chemistry, Manufacturing, and Controls (CMC) at Genesis Therapeutics

- Company: Genesis Therapeutics
- What the company does: Genesis pairs frontier AI with world-class drug hunters to discover small molecule medicines. Built on Pearl and GEMS. Partnered with Gilead and Incyte. Backed by a16z.
- Company website: https://www.genesis.ml
- Type: Startups
- Level: Principal and up
- Location: San Diego, CA
- Work setup: On-site
- Posted: 2026-09-14
- Apply by: 2026-10-29
- Apply: https://jobs.ashbyhq.com/genesis-molecular-ai/f5809624-8707-43d0-8425-cab8be39f71b
- Page: https://www.1752.vc/careers/jobs/genesis-therapeutics-senior-executive-director-of-chemistry-manufacturing-and-co/

## About the role

Strategic Portfolio Leadership: Establish and execute the global CMC strategy for the small molecule discovery and development pipeline, ensuring seamless transition from lead optimization to IND/CTA enablement. Drug Substance (DS) Development & Scale-Up: Oversee phase-appropriate process chemistry, route scouting, crystalline form screening/polymorph evaluation, and scale-up strategies for critical active pharmaceutical ingredients (APIs).

Tags: R&D