# Cheminformatics & Synthesis Prediction at Ginkgo Bioworks

- Company: Ginkgo Bioworks
- What the company does: Build autonomous labs to accelerate biotech R&D. Program biology like software. Run experiments on our cloud lab or build your own. Trusted by 130+ customers. Backed by SoftBank VF and Felicis.
- Company website: https://www.ginkgo.bio/
- Type: Startups
- Level: Mid level
- Location: Boston, Massachusetts
- Work setup: On-site
- Posted: 2026-08-25
- Apply by: 2026-10-12
- Apply: https://job-boards.greenhouse.io/ginkgobioworks/jobs/5220505007
- Page: https://www.1752.vc/careers/jobs/ginkgo-bioworks-cheminformatics-and-synthesis-prediction/

## About the role

We are hiring a Senior Engineer I, Cheminformatics to develop and operate the cheminformatics workflows behind Ginkgo’s makeable chemical space and reaction-prediction capabilities.

## What they're looking for

- Strong practical experience in cheminformatics and reaction prediction, including experience with retrosynthesis, reaction-condition prediction, synthetic accessibility, or related workflows
- Experience working with reaction SMARTS, functional-group classification, molecular representations, and chemical structure data
- Experience working with large chemical or vendor building-block catalogs and understanding the trade-offs involved in coverage, scale, and data quality
- Strong Python skills and experience writing code that others can run and maintain
- Familiarity with service-oriented software, Docker, environment-based configuration, and data pipelines
- Working knowledge of common medicinal-chemistry synthetic transformations and the ability to collaborate effectively with synthetic chemists

Tags: Datapoints Small Molecule Developability