# Senior Scientist I/II, In Vitro Pharmacology at Gordian Biotechnology

- Company: Gordian Biotechnology
- What the company does: Are you ready to turn novel, in vivo-validated targets into small molecule drug programs — building the assays, screening cascades and human-relevant models that decide which chemistry moves forward? Gordian is the leader in applying in vivo screening for... Backed by Stanford.
- Company website: https://gordian.bio
- Type: Startups
- Level: Senior
- Location: South San Francisco, CA
- Work setup: On-site
- Pay: $138K to $193K base salary per year (USD)
- Posted: 2026-10-30
- Apply by: 2026-12-14
- Apply: https://ats.rippling.com/gordian-biotechnology/jobs/d88bfcd7-4165-4ae1-a3c8-e2810e546bde?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/gordian-biotechnology-senior-scientist-i-ii-in-vitro-pharmacology/

## About the role

Your mission is to make three things work across our obesity, kidney (CKD/DKD) and heart failure (HFpEF) programs: Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Experience across more than one of kidney, cardiac and metabolic biology
- Target engagement and biophysical methods such as CETSA, NanoBRET or SPR
- First-in-class target experience, with no prior chemistry or tool compounds
- Lab automation, liquid handling or high-content imaging
- Advanced human cell models: iPSC-derived cells, 3D cultures or organoids, engineered heart tissue, kidney organoids or microphysiological systems
- Understanding of PK/PD and in vitro to in vivo translation in cardio-renal disease

Tags: Ex Vivo

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/gordian-biotechnology-senior-scientist-i-ii-in-vitro-pharmacology/