# Staff HPC Infrastructure Engineer at Guardant Health

- Company: Guardant Health
- What the company does: Guardant Health is a leading precision medicine company focused on transforming patient care and conquering cancer with data. Backed by Khosla, Lightspeed and Sequoia.
- Company website: https://guardanthealth.com/
- Type: Startups
- Level: Senior
- Location: Palo Alto, CA
- Work setup: On-site
- Pay: $173K to $238K base salary per year (USD)
- Posted: 2026-09-11
- Apply by: 2026-10-26
- Apply: https://gh.wd1.myworkdayjobs.com/en-US/gh/job/Palo-Alto-CA/Staff-HPC-Infrastructure-Engineer_R-101154-1
- Page: https://www.1752.vc/careers/jobs/guardant-health-staff-hpc-infrastructure-engineer/

## About the role

You enjoy an agile, very fast paced and highly technical environment. You are a self-driven, accomplished technologist who strives to continually improve your skills as the HPC landscape evolves and the computational infrastructure scales. You are dedicated to engineering excellence yet pragmatic and flexible. You have the ability to maintain the day-to-day support SLA while running various key projects that move the business forward.

## What they're looking for

- Bachelor’s degree in Computer Science or a related field with 8–12 years of relevant experience, Master’s degree with 6–8 years of relevant experience, or PhD with 3–5 years of relevant experience
- Strong experience in systems and/or infrastructure engineering, including Linux/Unix administration and TCP/IP networking
- Hands-on experience with automation tools, such as Ansible or equivalent technologies
- Experience with high-performance networking technologies, such as InfiniBand, RoCE, RDMA, or equivalent, including troubleshooting in production environments
- Experience supporting large-scale data storage and high-performance computing (HPC)/compute environments
- Experience working with both on-premise and cloud-based infrastructure, such as AWS, Google Cloud Platform (GCP), Azure, or similar environments