# Research Leader (Toxicology), Cambridge, MA at Isomorphic Labs

- Company: Isomorphic Labs
- What the company does: Isomorphic Labs is building a future where frontier AI can help to unlock deeper scientific insights, faster breakthroughs, and life-changing medicines. Backed by GV.
- Company website: https://www.isomorphiclabs.com
- Type: Startups
- Level: Mid level
- Location: Cambridge, MA
- Work setup: On-site
- Posted: 2026-09-11
- Apply by: 2026-10-26
- Apply: https://job-boards.greenhouse.io/isomorphiclabs/jobs/6188302004
- Page: https://www.1752.vc/careers/jobs/isomorphic-labs-research-leader-toxicology-cambridge-ma/

## About the role

As a Toxicology Lead, you will develop the safety assessment strategy of drug discovery and development projects from inception to regulatory submission. Working closely with the drug design platforms (small molecules and biologics), you will drive the optimisation of Iso’s assets with an AI-first approach in mind.

## What they're looking for

- Design and implement safety assessment strategies with an AI-first approach to support small molecules and biologics drug discovery projects
- Design screening cascades and mechanistic experiments to support project progression in a data-driven manner
- Develop SAR understanding of toxicology main liabilities to optimise chemical and biological matter where needed
- Define regulatory safety assessment packages to support successful acceptance by regulatory agencies
- Author toxicology sections of regulatory documents
- Partner with Machine Learning colleagues to build the predictive toxicology aspects of the drug design platform and identify, generate and analyse data from which to develop and improve predictive toxicology models

Tags: DDMR