# Associate Director/Director of Preclinical Development at Kernal Biologics

- Company: Kernal Biologics
- What the company does: Kernal biologics is an onco-selective mRNA therapeutics company located in Cambridge, MA. Backed by Y Combinator.
- Company website: https://www.kernalbio.com/
- Type: Startups (AI role)
- Level: Principal and up
- Location: Boston, MA
- Work setup: On-site
- Posted: 2026-08-12
- Apply by: 2026-10-08
- Apply: https://job-boards.greenhouse.io/kernalbio/jobs/7855192003
- Page: https://www.1752.vc/careers/jobs/kernal-biologics-associate-director-director-of-preclinical-development/

## About the role

Kernal Bio is seeking an experienced leader with deep expertise in immunology to lead our mRNA therapeutics efforts. This person will report to the Senior Vice President of R&D and will be responsible for leading preclinical development activities in immunology. In addition, this person will work closely with computational biology and mRNA delivery leadership to execute on company goals. The successful candidate must be able to work in a fast-paced and highly dynamic start-up environment.

## What they're looking for

- Comprehensive knowledge of preclinical development in autoimmune diseases, with preferred familiarity with immuno-oncology (e.g., CAR-T)
- Expertise in state-of-the-art methods for exploring cancer cell–immune cell interactions and assay development for mechanistic characterization of development candidates
- Proven track record of scientific accomplishments, demonstrated by publications, patent applications, and key contributions to Go/No-Go decisions
- Hands-on experience with multi-parameter flow cytometry, qPCR, and Western blotting
- Familiarity with single-cell sorting and deep immune profiling (including multiplex approaches)
- Strong passion for innovative research and a desire to make a clinical impact with mRNA therapeutics

Tags: R&D