# Medical Director, Early Phase Clinical Development at Latigo Biotherapeutics

- Company: Latigo Biotherapeutics
- What the company does: Backed by 5AM Ventures.
- Company website: https://latigobio.com
- Type: Startups
- Level: Principal and up
- Location: San Francisco, California
- Work setup: On-site
- Pay: $300K to $330K base salary per year (USD)
- Posted: 2026-09-08
- Apply by: 2026-10-23
- Apply: https://latigobio.bamboohr.com/careers/65
- Page: https://www.1752.vc/careers/jobs/latigo-biotherapeutics-medical-director-early-phase-clinical-development/

## About the role

The Medical Director will support the planning, execution, oversight, and interpretation of Phase 1 and clinical pharmacology studies across the company's development programs. This role will work closely with Clinical Pharmacology, Clinical Operations, Statistics, Pharmacovigilance, and Regulatory teams to provide medical leadership for first-in-human and other early clinical studies, including SAD/MAD, food effect, thorough QT (TQT), drug-drug interaction (DDI), hepatic impairment, and renal impairment studies.

## What they're looking for

- Serve as Medical Monitor for Phase 1 and clinical pharmacology studies
- Provide medical oversight for study conduct, including review of adverse events, serious adverse events, laboratory abnormalities, and emerging safety data
- Partner closely with Clinical Pharmacology on study design, dose escalation decisions, protocol development, and interpretation of clinical pharmacology data
- Provide medical input into study protocols, informed consent forms, investigator brochures, clinical study reports, and other clinical development documents
- Respond to investigator and site medical questions in a timely manner
- Participate in Safety Review Committees and other study governance activities

Tags: Clinical Development