# Sr. Director, Biostatistics at LeonaBio

- Company: LeonaBio
- What the company does: Backed by NEA.
- Company website: https://leonabio.com/
- Type: Startups
- Level: Principal and up
- Location: Remote (US)
- Work setup: Remote
- Pay: $270K to $290K base salary per year (USD)
- Posted: 2026-09-03
- Apply by: 2026-10-18
- Apply: https://leonabio.bamboohr.com/careers/81
- Page: https://www.1752.vc/careers/jobs/leonabio-sr-director-biostatistics/

## About the role

LeonaBio is seeking a Senior Director, Biostatistics to provide strategic and hands-on leadership across clinical development programs. Reporting to the Chief Medical Officer, this role will be responsible for shaping statistical strategy throughout the drug development lifecycle, from study design and analysis through data interpretation, regulatory submissions, and health authority interactions.

## What they're looking for

- Provide statistical leadership across clinical development programs, including study design, endpoint selection, sample size and power calculations, randomization, analysis strategy, and interpretation of clinical data
- Partner with Clinical Development and other cross-functional teams on protocol development, statistical analysis plans (SAPs), study design decisions, and overall development strategy
- Lead or oversee statistical analyses and deliverables across clinical trials, including tables, listings, figures (TLFs), clinical study reports, and other key clinical and regulatory documents
- Provide statistical expertise for interim analyses, Data Safety Monitoring Boards (DSMBs), and other study oversight activities as appropriate
- Oversee external biostatistics and statistical programming partners, including CRO selection and management, scope, timelines, quality, and deliverables
- Represent Biostatistics on cross-functional program teams and serve as a trusted statistical advisor to Clinical Development, Regulatory, Data Management, Clinical Operations, Medical, and senior leadership