# Staff / Principal Security Engineer, AI Safety and Security at Lila Sciences

- Company: Lila Sciences
- What the company does: LILA has created the world's first Operating System for Science powered by Scientific Superintelligence™. Backed by General Catalyst.
- Company website: https://www.lila.ai/
- Type: Startups (AI role)
- Level: Principal and up
- Location: Cambridge, MA USA; London, UK; San Francisco, CA USA
- Work setup: On-site
- Posted: 2026-10-16
- Apply by: 2026-11-30
- Apply: https://job-boards.greenhouse.io/lilasciences/jobs/4429015009?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/lila-sciences-staff-principal-security-engineer-ai-safety-and-security/

## About the role

Lila is developing AI systems for scientific discovery, connecting advanced models with scientific tools and automated laboratories. As these systems become more capable, we need to understand how they could be misused or compromised, which protections matter most, and how to establish that those protections work together. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- A record of resolving consequential security problems. You have investigated ambiguous risks, challenged designs and followed improvements through to validation, including work involving several teams
- Strong technical judgment. You can examine unfamiliar systems, scrutinize code and configurations where relevant, and use technical investigation or testing to distinguish plausible claims from demonstrated protection
- Curiosity about AI safety and scientific systems. You want to understand how model capabilities and safeguards are evaluated, can learn unfamiliar domains quickly, and reason carefully when evidence is incomplete
- Clear writing and effective collaboration. You can explain a technical argument precisely, work through disagreements with specialists and turn a complex investigation into an actionable recommendation

Tags: AI

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/lila-sciences-staff-principal-security-engineer-ai-safety-and-security/