# Director, Clinical Business Operations at Maze Therapeutics

- Company: Maze Therapeutics
- What the company does: Backed by a16z and GV.
- Type: Startups
- Level: Principal and up
- Location: South San Francisco, CA
- Work setup: On-site
- Pay: $222K to $271K base salary per year (USD)
- Posted: 2026-08-04
- Apply by: 2026-10-08
- Apply: http://www.mazetx.com/careers/?gh_jid=8659939002
- Page: https://www.1752.vc/careers/jobs/maze-therapeutics-director-clinical-business-operations/

## About the role

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As Director, Clinical Business Operations, you will serve as a strategic business partner to the Head of Clinical Operations and the Clinical Development organization.

## What they're looking for

- Bachelor's degree in Business, Finance, Life Sciences, Healthcare Administration, or a related field
- 10–12+ years of experience in Clinical Business Operations, Clinical Finance, Strategic Sourcing, Clinical Operations, or related business roles within biotechnology, pharmaceutical, or CRO organizations
- Extensive experience developing and managing global clinical trial budgets across all phases of clinical development
- Demonstrated success negotiating CRO, vendor, and investigator site budgets, including Master Service Agreements, work orders, study budgets, site budgets, and change orders
- Strong understanding of clinical development, outsourcing models, fair market value methodologies, vendor contracting, and financial planning processes
- Experience partnering closely with Finance on monthly accruals and forecasting, annual budgeting, long-range planning, and financial governance

Tags: Clinical Operations