# Director, Clinical Operations at Maze Therapeutics

- Company: Maze Therapeutics
- What the company does: Backed by a16z and GV.
- Type: Startups
- Level: Principal and up
- Location: South San Francisco, CA
- Work setup: On-site
- Pay: $232K to $283K base salary per year (USD)
- Posted: 2026-08-04
- Apply by: 2026-10-08
- Apply: http://www.mazetx.com/careers/?gh_jid=8659924002
- Page: https://www.1752.vc/careers/jobs/maze-therapeutics-director-clinical-operations/

## About the role

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As Director of Clinical Operations, you will serve as Study Lead for a complex, global pivotal Phase 3 program within our chronic kidney disease (CKD) clinical development portfolio.

## What they're looking for

- A Bachelor’s degree in a scientific or health-related field with 10–12+ years of clinical operations experience, including study leadership of Phase I–III trials
- Demonstrated success as the end-to-end operational lead for a complex large global Phase 3 study, including feasibility, startup, enrollment, study conduct, close-out, and inspection readiness
- Experience leading clinical trials in renal, or cardiometabolic diseases is strongly preferred
- Proven experience managing and developing teams, including coaching, mentoring, delegation, and supporting the growth of both managers and early-career professionals
- Expertise in global regulatory requirements (e.g., FDA, EMA, ANVISA, AMA, ICH-GCP), including direct experience supporting audits, inspections, and inspection-readiness activities
- Exceptional critical thinking and strategic judgment, with the ability to synthesize incomplete or evolving information, recommend a clear path forward, and influence decisions at study-team and executive levels

Tags: Clinical Operations