# Oversight Director, Clinical Operations at Maze Therapeutics

- Company: Maze Therapeutics
- What the company does: Backed by a16z and GV.
- Type: Startups
- Level: Principal and up
- Location: South San Francisco, CA
- Work setup: On-site
- Pay: $232K to $283K base salary per year (USD)
- Posted: 2026-08-04
- Apply by: 2026-10-08
- Apply: http://www.mazetx.com/careers/?gh_jid=8659934002
- Page: https://www.1752.vc/careers/jobs/maze-therapeutics-oversight-director-clinical-operations/

## About the role

At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As an Oversight Director, Clinical Operations supporting an asset spanning our CKD and PKU portfolio, you will provide strategic and operational direction across the full development lifecycle.

## What they're looking for

- Demonstrated success providing operational direction across multiple studies within a development program, driving strategy, execution, and delivery of key program milestones
- Proven experience guiding and developing high-performing Clinical Operations teams, including direct management, coaching, and mentoring of Study Leads and other Clinical Operations professionals
- Deep expertise in global clinical trial operations, including FDA, EMA, ICH-GCP, and other applicable regulatory requirements, with a strong track record of maintaining inspection readiness
- Extensive experience developing and overseeing CRO and vendor partnerships, including governance, performance management, contract negotiations, and budget accountability
- Strong financial acumen with experience managing large, complex clinical trial budgets, forecasting, and resource planning
- Demonstrated ability to identify operational risks, facilitate cross-functional problem-solving, and contribute to strategic planning in a fast-paced development environment

Tags: Clinical Operations