# Senior Clinical Trial Manager, Early Development at Maze Therapeutics

- Company: Maze Therapeutics
- What the company does: Backed by a16z and GV.
- Type: Startups
- Level: Senior
- Location: South San Francisco, CA
- Work setup: On-site
- Posted: 2025-11-26
- Apply by: 2026-10-08
- Apply: http://www.mazetx.com/careers/?gh_jid=8310728002
- Page: https://www.1752.vc/careers/jobs/maze-therapeutics-senior-clinical-trial-manager-early-development/

## About the role

At Maze Therapeutics, we believe that precision medicine has the power to transform the lives of patients with both common and rare diseases . As a Senior Clinical Trial Manager (Sr. CTM) at Maze Therapeutics, you’ll play a hands-on role in driving the execution of our clinical trials. You’ll have the opportunity to lead Early Development studies, work cross-functionally with internal teams and external partners, and ensure studies run efficiently and with the highest quality standards.

## What they're looking for

- Demonstrated experience managing Phase I and early development trials across healthy volunteer and patient populations, including first-in-human and bridging studies
- Strong understanding of Clinical Pharmacology principles, including pharmacokinetics, pharmacodynamics, bioanalytical sampling, and PK data workflows
- Familiarity with regulatory guidelines (FDA, EMA, ICH-GCP)
- Strong executional leadership, problem-solving skills, and ability to manage cross-functional teams at the study level
- A startup mindset, willingness to roll up sleeves, and ability to work in a fast-paced, evolving, and collaborative team environment
- Excellent communication skills and the ability to manage cross-functional relationships effectively

Tags: Clinical Operations