# Lead Bioinformatics & Machine Learning Scientist at Natera

- Company: Natera
- What the company does: Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care. Backed by Lightspeed and Sequoia.
- Company website: https://natera.com/
- Type: Startups (AI role)
- Level: Senior
- Location: US Remote
- Work setup: Remote
- Posted: 2026-11-04
- Apply by: 2026-12-19
- Apply: https://job-boards.greenhouse.io/natera/jobs/6239427004?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/natera-lead-bioinformatics-and-machine-learning-scientist/

## About the role

Natera is seeking a Lead Bioinformatics & Machine Learning Scientist to join our Bioinformatics Research team and help build the machine learning models behind Natera's tissue-free, methylation-based assay. These will be the models that detect cancer in the minimal residual disease (MRD) setting and help inform treatment selection. The ideal candidate brings a strong background in algorithm development, genomics, sequencing data processing, and applied machine learning. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- PhD in Computer Science, Bioinformatics, Computational Biology, or a related quantitative field with a strong emphasis on cancer epi/genomics and 4 to 8+ years of experience post-PhD
- Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows
- Experience in algorithm development and data analysis, including applying and evaluating statistical methods
- Demonstrated experience in developing core ML models, including generalized linear models, kernel methods, tree-based algorithms, and neural networks, with a focus on biological data (e.g., DNA sequencing data)
- Strong quantitative reasoning and data analysis skills, with a demonstrated ability to apply them effectively to relevant scientific problems
- Familiarity with public databases such as TCGA, COSMIC, or OncoKB

Tags: Molecular Biology Informatics &...

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/natera-lead-bioinformatics-and-machine-learning-scientist/