# Senior Product Manager, Oncology at Natera

- Company: Natera
- What the company does: Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care. Backed by Lightspeed and Sequoia.
- Company website: https://natera.com/
- Type: Startups
- Level: Senior
- Location: Austin, TX; Pleasanton, CA; San Carlos, CA; South San Francisco
- Work setup: On-site
- Posted: 2026-09-15
- Apply by: 2026-10-30
- Apply: https://job-boards.greenhouse.io/natera/jobs/6193126004
- Page: https://www.1752.vc/careers/jobs/natera-senior-product-manager-oncology/

## About the role

About the Role: The Senior Product Manager, Oncology leads product development and commercial scale for Signatera, Natera's market-leading tumor-informed minimal residual disease (MRD) assay. This role owns laboratory turnaround time, throughput, and process stability across core lab sites. You will drive the change control review (CCR) pipeline end-to-end from root-cause investigation through requirements authorship, core team leadership, and post-launch hypercare monitoring.

## What they're looking for

- Bachelor’s degree in life sciences, physical sciences, statistics, or engineering. Master’s or PhD preferred
- Minimum 5 years of professional experience, including 2-3 years in product management, commercialization, or strategic consulting within diagnostics, medical devices, or oncology
- Experience with products delivered as laboratory services strongly preferred
- Demonstrated experience driving data-driven process improvements using operational data and VOC to eliminate failure modes across the sample lifecycle
- Hands-on experience with quality systems (CAPA, nonconformance, change control) in a CLIA/CAP lab environment preferred
- Experience with SQL, Snowflake, Statistical Process Control (SPC), or continuous improvement frameworks (Lean, Six Sigma) preferred

Tags: Oncology Product Management