# Senior/Principal Scientist, Translational Biomarkers at NewLimit

- Company: NewLimit
- What the company does: NewLimit is extending human healthspan by unlocking regenerative potential. Backed by Kleiner Perkins.
- Company website: https://www.newlimit.com/
- Type: Startups
- Level: Principal and up
- Location: South San Francisco
- Work setup: On-site
- Pay: $155K to $200K base salary per year (USD)
- Posted: 2026-04-17
- Apply by: 2026-10-08
- Apply: https://job-boards.greenhouse.io/newlimit/jobs/5969886004
- Page: https://www.1752.vc/careers/jobs/newlimit-senior-principal-scientist-translational-biomarkers/

## About the role

NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development. In this role, you will lead the discovery, development, and qualification of pharmacodynamic (PD) biomarker assays that characterize the biological activity of our mRNA-LNP medicines in preclinical and IND-enabling studies.

## What they're looking for

- PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years)
- Strong working knowledge of bioanalytical method qualification/validation principles for PD biomarker measurements, including familiarity with ICH M10 guidelines and fit-for-purpose frameworks
- History of delivering results for bioanalytical projects -- you've discovered a PD biomarker or built an assay and solved all the problems along the way
- Experience with primary cell culture and tissue-derived sample workflows

Tags: Single Cell Technology