# Senior/Principal Scientist, Medicinal Chemistry at Nurix AI

- Company: Nurix AI
- What the company does: AI agents that run your enterprise workflows and get measurably better over time. 150+ enterprises live in production across retail, insurance, and financial services. Backed by Accel and General Catalyst.
- Company website: https://www.nurix.ai/
- Type: Startups (AI role)
- Level: Principal and up
- Location: Brisbane, California, United States
- Work setup: On-site
- Pay: $166K to $177K base salary per year (USD)
- Posted: 2026-10-22
- Apply by: 2026-12-06
- Apply: https://job-boards.greenhouse.io/nurix/jobs/8910067002?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/nurix-ai-senior-principal-scientist-medicinal-chemistry/

## About the role

We are seeking a talented and highly motivated individual with a strong background in synthetic organic chemistry to join our medicinal chemistry group in the pursuit of degrader-based small molecules to treat patients with unmet medical needs. This individual will design and synthesize novel chemical entities optimized for potency, selectivity, pharmacokinetics and in vivo efficacy, and will engage in rational structure-based drug discovery enabled by our computational and structural biology groups. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Ph.D. in synthetic organic chemistry with 8 – 10+ years pharmaceutical medicinal chemistry industrial experience
- Track record of delivering advanced leads/ development candidates
- Expert in organic synthesis, knowledgeable of the current literature, with strong synthetic problem-solving skills
- Proven leadership capability in a cross-functional team setting, either as project team leader or co-lead
- Ability to make inventive contributions towards new chemical target structures or templates for programs and evaluate early screening or literature hits
- Strong skills in gathering, documenting, and analyzing information from competitive sources such as patents and meetings and using this information to guide program strategy

Tags: Medicinal Chemistry

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/nurix-ai-senior-principal-scientist-medicinal-chemistry/