# Senior Manager/Associate Director, External Manufacturing at Obsidian Therapeutics

- Company: Obsidian Therapeutics
- What the company does: Backed by GV.
- Type: Startups
- Level: Principal and up
- Location: Bedford, MA (HYBRID)
- Work setup: Hybrid
- Posted: 2026-08-19
- Apply by: 2026-10-08
- Apply: https://job-boards.greenhouse.io/obsidiantherapeutics/jobs/6144134004
- Page: https://www.1752.vc/careers/jobs/obsidian-therapeutics-senior-manager-associate-director-external-manufacturing/

## About the role

We are looking for a highly motivated Senior Manager/Associate Director External Manufacturing, with a strong background in CDMO management of viral vector and ancillary materials production. As a key contributor within the External Manufacturing organization, you’ll lead front-line oversight of viral vector and ancillary material production, helping to drive the development of our first autologous cell therapy program targeting solid tumors In addition, you’ll establish a new phase appropriate manufacturing...

## What they're looking for

- Bachelor's Degree in Life Sciences, Engineering, or related discipline with, Senior Manager 8+ (MS 6+), Associate Director 10+ (MS 8+) years of experience in manufacturing or MS&T roles in the biotech/pharma industry
- Extensive experience designing and implementing batch records, EBRs, and MES integrated systems
- Deep experience in quality systems, deviation management, root cause analysis, change control, and risk management in a GMP environment
- Proven application of Lean manufacturing and operational excellence tools and techniques to improve manufacturing cycle times and right first-time execution
- Strong understanding of GMP regulations, quality requirements, and global regulatory expectations for advanced therapies
- Proficiency in developing and managing SOWs, change orders, contract negotiations, CDMO budget planning, financial reporting, and budget management

Tags: Technical Operations