# Vice President of Information Technology at Olema

- Company: Olema
- What the company does: Olema Oncology is a clinical-stage biopharmaceutical company developing novel therapies to transform treatment for metastatic breast cancer and beyond. Backed by Lightspeed.
- Company website: https://olema.com/
- Type: Startups
- Level: Principal and up
- Location: San Francisco, California
- Work setup: On-site
- Posted: 2026-09-22
- Apply by: 2026-11-06
- Apply: https://job-boards.greenhouse.io/olema/jobs/6205816004
- Page: https://www.1752.vc/careers/jobs/olema-vice-president-of-information-technology/

## About the role

Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in Q1 2027 which, if positive, could lead to our first potential approval and commercial launch in 2028.

## What they're looking for

- Define and execute a multi-year enterprise IT strategy and applications roadmap aligned with business goals across research, development, commercial, and corporate functions
- Set efficient and scalable architecture, integration, cloud, SaaS, data, and technology lifecycle standards that support growth without unnecessary complexity
- Establish a strategic and effective IT operating model, including internal capabilities, outsourced services, governance, and decision rights
- Establish disciplined intake, prioritization, funding, and delivery processes that make value, cost, risk, capacity, and dependencies visible
- Advise the Executive Committee on technology investments, performance, cybersecurity, and risk
- O wn IT budgets, vendors, and major implementation partners

Tags: Business and Operations