# Sr. Scientist/Principal Scientist, CMC Analytical Development at Orca Bio

- Company: Orca Bio
- What the company does: Orca Bio is helping to deliver the promise of cell therapy to patients without compromise. Backed by Lightspeed and Felicis.
- Company website: https://orcabio.com/
- Type: Startups
- Level: Principal and up
- Location: Sacramento, CA
- Work setup: On-site
- Pay: $140K to $170K base salary per year (USD)
- Posted: 2026-10-13
- Apply by: 2026-11-27
- Apply: https://jobs.lever.co/orcabiosystems/e130af89-b0fa-460d-b525-dcec3adc8df7?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/orca-bio-senior-principal-scientist-cmc-analytical-development/

## About the role

In this role, you will own analytical development for potency, mechanism of action, product characterization, and release testing methods supporting early- and late-stage cell therapy programs. You will also author CMC analytical content for BLA submissions and help prepare our programs for commercialization. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- PhD in Pharmaceutical Sciences, Biology, Immunology, Cell Biology, or a related field with 8+ years of relevant industry experience
- Proven track record of team/group leadership
- Substantial expertise in flow cytometry and cell-based assay technologies
- Experience with immune functional assays in cell therapy and/or biologics analytical development or quality control laboratories
- Working knowledge of QC and cGMP requirements for the biopharmaceutical industry, including relevant USP methodologies and ICH guidelines
- Experience working with and leading cross-functional teams, such as CMC and clinical development teams

Tags: Chemistry, Manufacturing & Controls

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/orca-bio-senior-principal-scientist-cmc-analytical-development/