# Director, Clinical Science at Pathos

- Company: Pathos
- What the company does: Drug development shouldn’t be guesswork, not when patients are waiting. Pathos is building a next-generation biotech with AI at the core. Not as a feature, but as the operating system for how medicines get developed. Backed by NEA.
- Company website: https://pathos.com/
- Type: Startups
- Level: Principal and up
- Location: New York City, NY
- Work setup: On-site
- Pay: $200K to $240K base salary per year (USD)
- Posted: 2026-06-18
- Apply by: 2026-10-08
- Apply: https://ats.rippling.com/pathos/jobs/9a2789d2-4403-4db2-8878-2d93a3c38318
- Page: https://www.1752.vc/careers/jobs/pathos-director-clinical-science/

## About the role

The Director, Clinical Science is a hands-on member of the Clinical Development team, responsible for the day-to-day scientific execution of Pathos oncology programs across active Phase 1 and Phase 2 trials. You own protocol development, data review, clinical document authorship, and site-level scientific support from study startup through closeout.

## What they're looking for

- Author and own study protocols from first draft through amendments, including study design, eligibility criteria, endpoint selection, and safety monitoring plans
- Write and maintain Investigator Brochures, informed consent forms, Clinical Study Reports, and briefing documents in partnership with Clinical Operations and Medical Writing
- Direct AI agents to compile source data, structure document drafts, and run quality checks, then apply your scientific judgment to finalize each deliverable
- Conduct ongoing review of safety and efficacy data across active studies, including eligibility confirmation, protocol deviation assessment, and adverse event review
- Prepare materials and lead deliverables for data monitoring committees and other clinical review bodies
- Collaborate with data management on eCRF development, edit check design, and database lock activities

Tags: Clinical