# Associate Scientist I, Biochemistry at Pliant Therapeutics

- Company: Pliant Therapeutics
- What the company does: Pliant Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel therapies for the treatment of fibrosis and related diseases. Backed by Menlo Ventures.
- Company website: https://pliantrx.com
- Type: Startups
- Level: Associate
- Location: South San Francisco, CA
- Work setup: On-site
- Pay: $125K to $138K base salary per year (USD)
- Posted: 2026-11-06
- Apply by: 2026-12-21
- Apply: https://job-boards.greenhouse.io/plianttherapeuticsinc/jobs/8197938003?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/pliant-therapeutics-associate-scientist-i-biochemistry/

## About the role

At Pliant, we believe differentiated science can make a meaningful impact. We see our success as a direct result of the central role that each team member plays in advancing our mission to develop therapies that target the disease at its source. We are seeking creative, curious and collaborative individuals who dare to succeed , are committed to making an important impact on patient’s lives and will help us build one Pliant ! Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- BS in Biochemistry, Biology, Chemistry or a related field with 7+ years of relevant biopharmaceutical industry experience, or an MS with 5+ years
- Direct, hands-on experience developing and running AlphaScreen and/or AlphaLISA assays, including troubleshooting signal window, hook effect and compound interference
- Demonstrated track record of developing and validating biochemical binding assays for medium- to high-throughput screening in 384- and/or 1536-well formats
- Proficiency with liquid handlers and plate-based workflows (e.g., i5 BIOMEK, Tempest or similar) and multimode plate readers capable of Alpha detection (e.g., EnVision, PHERAstar)
- Familiarity with high-content imaging equipment such as the Operetta CLS
- Sound understanding of binding kinetics and pharmacology: Kd, Ki, IC50, Cheng–Prusoff, and the assumptions behind them

Tags: Chemistry

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/pliant-therapeutics-associate-scientist-i-biochemistry/