# Executive Director / Vice President, Biology & Translational Pharmacology at Profluent

- Company: Profluent
- What the company does: The next frontier is authoring new biology, and with AI, we have the power to write the future—creating solutions that transform medicine, agriculture, and beyond. Backed by Insight and Air Street.
- Company website: https://www.profluent.bio/
- Type: Startups (AI role)
- Level: Principal and up
- Location: Emeryville, California, United States; On-site
- Work setup: On-site
- Posted: 2026-07-02
- Apply by: 2026-10-08
- Apply: https://job-boards.greenhouse.io/profluent/jobs/5289412008
- Page: https://www.1752.vc/careers/jobs/profluent-executive-director-vice-president-biology-and-translational-pharmacolo/

## About the role

Profluent is seeking an exceptional Executive Director / Vice President, Biology & Translational Pharmacology to lead the scientific strategy and execution of our gene editing therapeutic portfolio. You will help realize the full potential of Profluent’s AI-designed, customized base editors by advancing a defined initial pipeline of genetic medicines for severe inborn metabolic diseases.

## What they're looking for

- PhD, MD, DVM, PharmD, or equivalent advanced degree in pharmacology, molecular biology, genetics, physiology, hepatology, bioengineering, medicine, or a related discipline
- PhD in related discipline with significant (12+ years) biopharma R&D experience, with a strong track record in genetic medicines, liver biology, translational pharmacology, and preclinical development
- Deep experience with genetic medicines or advanced therapeutic modalities, such as RNAi, antisense oligonucleotides, mRNA/LNP therapeutics, gene therapy, genome editing, or related platforms
- Deep understanding of liver biology and metabolic disease, with the ability to connect human genetics, disease biology, pharmacology, biomarkers, translational models, and development strategy
- Extensive experience with rare liver diseases, lipid biology, hepatology, fibrosis biology, and / or metabolic liver disease
- Demonstrated ability to lead multidisciplinary scientific teams, including direct management of senior scientists or functional leaders and leadership of matrixed drug-discovery project teams

Tags: Biology