# Lead Scientist / Associate Director, Bioinformatics and Data Science at Profluent

- Company: Profluent
- What the company does: The next frontier is authoring new biology, and with AI, we have the power to write the future—creating solutions that transform medicine, agriculture, and beyond. Backed by Insight and Air Street.
- Company website: https://www.profluent.bio/
- Type: Startups (AI role)
- Level: Principal and up
- Location: Emeryville, California, United States; Hybrid (2-3 days on-site)
- Work setup: Hybrid
- Posted: 2025-11-13
- Apply by: 2026-10-08
- Apply: https://job-boards.greenhouse.io/profluent/jobs/4983485008
- Page: https://www.1752.vc/careers/jobs/profluent-lead-scientist-associate-director-bioinformatics-and-data-science/

## About the role

We’re seeking an experienced computational scientist to lead the design, development, and operation of the NGS analysis platform that powers Profluent’s gene editing, protein design, and therapeutic programs. You’ll work at the intersection of computational biology, software engineering, and experimental biology to build scalable systems that extract clear, actionable insights from large-scale sequencing data.

## What they're looking for

- PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field
- PhD with 5+ years or MS with 7+ years of industry experience applying NGS and computational analysis to gene or cell therapy development
- Deep expertise in the design, analysis, and interpretation of high-throughput sequencing assays
- Strong programming and quantitative analysis skills, particularly in Python
- Proven ability to translate complex sequencing data into clear biological insights and program decisions
- Experience partnering closely with experimental scientists to guide assay design, troubleshoot results, and define follow-up studies

Tags: Bioinformatics