# Director, Regulatory Affairs at Repertoire Immune Medicines

- Company: Repertoire Immune Medicines
- What the company does: Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease. Backed by SoftBank VF.
- Company website: https://www.repertoire.com/
- Type: Startups
- Level: Principal and up
- Location: Remote (US)
- Work setup: Remote
- Pay: $210K to $245K base salary per year (USD)
- Posted: 2026-09-15
- Apply by: 2026-10-30
- Apply: https://repertoireimmunemedicinesinc.applytojob.com/apply/zdZa0ApGoq/Director-Regulatory-Affairs
- Page: https://www.1752.vc/careers/jobs/repertoire-immune-medicines-director-regulatory-affairs/

## About the role

Repertoire Immune Medicines is seeking an experienced Director of Regulatory Affairs to serve as the company’s first internal Regulatory Affairs hire and regulatory lead for its clinical-stage oncology programs. The Director will own global regulatory strategy and execution across Phase 1 and Phase 2 development in the U.S., EU, and UK, partnering closely with Clinical Development, Clinical Operations, CMC, Quality, and external regulatory partners.

## What they're looking for

- Serve as the internal Regulatory Lead for Repertoire's clinical-stage oncology programs, developing and executing global regulatory strategy across Phase 1 and Phase 2 development
- Lead regulatory strategy and execution for INDs, CTAs, amendments, and other submissions supporting new and ongoing clinical studies
- Lead health authority interactions with FDA, EU regulatory authorities, and MHRA—including strategy development, briefing materials, meeting preparation, and agency correspondence
- Partner cross-functionally with Clinical Development, Clinical Operations, CMC, and Quality to embed regulatory strategy into development plans and program decisions
- Advise on clinical protocols, development plans, CMC changes, IND/IMPD content, product stability, and other issues arising during early clinical development
- Proactively identify regulatory risks and opportunities and develop practical, well-vetted strategies to address them