# Scientist II, mRNA Technologies at Repertoire Immune Medicines

- Company: Repertoire Immune Medicines
- What the company does: Repertoire Immune Medicines is a clinical-stage biotechnology company working to unlock and direct the remarkable power of the human immune system to prevent or treat cancer, as well as autoimmune and infectious disease. Backed by SoftBank VF.
- Company website: https://www.repertoire.com/
- Type: Startups
- Level: Mid level
- Location: Remote (US)
- Work setup: Remote
- Pay: $120K to $160K base salary per year (USD)
- Posted: 2026-10-27
- Apply by: 2026-12-11
- Apply: https://repertoireimmunemedicinesinc.applytojob.com/apply/Wumj1ZZYkq/Scientist-II-MRNA-Technologies?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/repertoire-immune-medicines-scientist-ii-mrna-technologies/

## About the role

We are seeking a highly skilled and motivated Scientist II to join Repertoire’s autoimmune tolerance induction team. Working with a dedicated team of scientists and research associates, you will help advance Repertoire’s novel immune tolerance modality across multiple indications. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Design and optimize the molecular components of mRNA molecules for antigen expression and presentation in immune cells, as well as in other tissue targets for systemic protein delivery
- Collaborate with preclinical biology and disease area teams on characterizing construct designs and payloads for functional activity across in vitro and in vivo models
- Establish, optimize, and innovate processes for scalable in vitro transcription (IVT) production and purification of mRNA for discovery and therapeutic applications
- Contribute to the development of analytical characterization methods for mRNA molecules and mRNA-LNP drug product with an eye toward tech transfer to a CRO/CDMO
- Ensure supply of in vivo grade mRNA and mRNA-LNP product to the tolerance team and throughout Repertoire
- Design and maintain the external supply chain for research grade plasmids for IVT production of mRNA


Source: 1752vc Careers, https://www.1752.vc/careers/jobs/repertoire-immune-medicines-scientist-ii-mrna-technologies/