# Associate Director, Computational Chemistry at Revolution Medicines

- Company: Revolution Medicines
- What the company does: Backed by GV.
- Type: Startups
- Level: Principal and up
- Location: Redwood City, California, United States
- Work setup: On-site
- Posted: 2026-10-15
- Apply by: 2026-11-29
- Apply: https://www.revmed.com/careers-list/?gh_jid=8034744003&utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/revolution-medicines-associate-director-computational-chemistry/

## About the role

We are seeking an accomplished and creative Associate Director to join our Computational Chemistry team, reporting to the Head of Computational Chemistry. A core priority of this role is to lead computational support for drug discovery programs, using structure-based drug design to guide compound design and optimization from hit finding through lead optimization. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Ph.D. in computational chemistry or a related field. 10+ years experience post PhD
- Expert knowledge of computational chemistry methods for protein-ligand analysis and molecular design, including docking, virtual screening, pharmacophore modeling, molecular dynamics, and free energy or quantum mechanical calculations
- Experience developing, validating, and applying AI/ML or data science approaches to drug discovery, with sound judgment in model evaluation, uncertainty, applicability, and experimental validation
- Strong scientific programming skills in Python or related languages, and experience with computational chemistry, cheminformatics, and machine learning software
- Demonstrated ability to set scientific priorities, develop work plans, coordinate resources, and lead scientists or cross-functional programs. Ability to influence senior stakeholders and communicate complex findings and recommendations clearly
- A collaborative leadership style, a record of mentoring scientists, and the ability to balance exploratory research with discovery timelines and deliverables

Tags: Digital Drug Discovery

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/revolution-medicines-associate-director-computational-chemistry/