# Senior Director, Head of Structural Biology at Revolution Medicines

- Company: Revolution Medicines
- What the company does: Backed by GV.
- Type: Startups
- Level: Principal and up
- Location: Redwood City, California, United States
- Work setup: On-site
- Posted: 2026-11-02
- Apply by: 2026-12-17
- Apply: https://www.revmed.com/careers-list/?gh_jid=8111438003&utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/revolution-medicines-senior-director-head-of-structural-biology/

## About the role

We are seeking a Senior Director, Head of Structural Biology, to lead the scientific strategy, team development, and operations of our Structural Biology group. The group integrates X-ray crystallography, NMR, and cryo-EM to advance oncology drug discovery through Revolution Medicines’ tri-complex molecular glue platform. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- PhD in structural biology, biophysics, biochemistry, or a related discipline, with 12+ years biotechnology or pharmaceutical industry experience and a demonstrated record of scientific and people leadership
- Proven ability to lead a structural biology group, develop scientific leaders, and translate research strategy into priorities, resource plans, and measurable outcomes across multiple discovery programs
- Deep expertise in at least one of X-ray crystallography, NMR, or cryo-EM, with sufficient breadth across all three to guide specialists, evaluate data critically, and develop an integrated experimental strategy
- Strong track record of applying structural biology to small molecule drug discovery in close partnership with medicinal chemistry, including translating structural findings into compound design and optimization decisions
- Expertise in protein-ligand and protein-protein interactions, complex assembly, and structure-function analysis, with the ability to integrate structural, biophysical, biochemical, and cellular evidence into testable mechanistic models
- Experience integrating structural methods with computational modeling, molecular simulation, or complementary biophysical approaches to explain molecular recognition and dynamics

Tags: Discovery Biology

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/revolution-medicines-senior-director-head-of-structural-biology/