# Senior Vice President, Chemistry at Rezo Therapeutics

- Company: Rezo Therapeutics
- What the company does: Backed by Norwest and a16z.
- Company website: https://rezotx.com/
- Type: Startups
- Level: Principal and up
- Location: San Francisco, CA
- Work setup: On-site
- Pay: $270K to $370K base salary per year (USD)
- Posted: 2026-10-27
- Apply by: 2026-12-11
- Apply: https://jobs.lever.co/rezotx/49fa0d4d-987a-41e1-8001-8a521603193e?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/rezo-therapeutics-senior-vice-president-chemistry-and-cmc/

## About the role

Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Own chemistry strategy and execution across the small-molecule portfolio, with particular focus on late-stage lead optimization, candidate quality, developability, and clear nomination criteria
- Drive rigorous development candidate selection, including definition of backup strategies and assessment of route scalability, formulation feasibility, and intellectual property
- Lead the CMC strategy for nominated candidates through IND-enabling studies and first-in-human readiness, spanning drug substance, drug product, analytical development, and phase-appropriate control strategies
- Provide accountable oversight of CROs and CDMOs: partner selection, scopes of work, technical decisions, budgets, quality, risk mitigation, technology transfer, and milestone delivery
- Build, mentor, and develop a high-performing internal chemistry organization while leveraging external capabilities, establish a culture of scientific rigor, transparent decision-making, urgency, and accountability
- Collaborate closely with biology, structural biology, computational sciences, pharmacology, and leadership to integrate emerging data and make disciplined portfolio decisions

Tags: Research & Development

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/rezo-therapeutics-senior-vice-president-chemistry-and-cmc/