# Senior HPC & GPU Infrastructure Engineer at Sciforium

- Company: Sciforium
- What the company does: Sciforium builds the next generation of AI models with unprecedented efficiency, privacy, and versatility. Backed by SignalFire.
- Company website: https://sciforium.com
- Type: Startups
- Level: Senior
- Location: San Francisco, CA
- Work setup: On-site
- Pay: $150K to $220K base salary per year (USD)
- Posted: 2026-10-06
- Apply by: 2026-11-23
- Apply: https://jobs.ashbyhq.com/Sciforium/840adeda-38a1-4ca4-b7c9-304f651e2e55?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/sciforium-senior-hpc-and-gpu-infrastructure-engineer/

## About the role

We are seeking a Senior HPC & GPU Infrastructure Engineer to take full ownership of the health, reliability, and performance of our GPU compute cluster. You will be the primary custodian of our high-density accelerator environment and the linchpin between hardware operations, distributed systems, and machine learning workflows. This role spans everything from hands-on Linux systems engineering and GPU driver bring-up to maintaining the ML software stack (CUDA/ROCm, PyTorch, JAX, vLLM). Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- 5+ years of experience in HPC, GPU cluster operations, Linux systems engineering, or similar roles
- Bachelor’s or Master’s degree in Computer Science, Computer Engineering, Electrical Engineering, or a related technical field
- Strong expertise with NVIDIA (H100/B200) or AMD (MI325x/MI355x) GPUs, including driver and kernel-level debugging
- Deep understanding of Linux internals, kernel modules, hardware bring-up, and systems performance tuning
- Experience with network security, including VPNs, iptables/firewalld, SSH, and identity management (LDAP/FreeIPA/AD)
- Proficiency in Bash and Python for scripting, automation, and workflow tooling

Tags: Engineering

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/sciforium-senior-hpc-and-gpu-infrastructure-engineer/