# Senior Engineering Manager, AI Platform at Sequencing

- Company: Sequencing
- What the company does: Sequencing is building the lifelong home for every genome on Earth and the foundational platform for the AI-native genomic era.

The human genome is the world’s most valuable untapped resource and one of the defining datasets of the 21st century. Backed by XRC Labs.
- Company website: https://sequencing.com
- Type: Startups (AI role)
- Level: Senior
- Location: Remote US
- Work setup: Remote
- Posted: 2026-08-25
- Apply by: 2026-10-14
- Apply: https://jobs.ashbyhq.com/sequencing/982e4ebd-6ee9-49fc-9bb1-ec53f4429cc0
- Page: https://www.1752.vc/careers/jobs/sequencing-senior-engineering-manager-ai-platform/

## About the role

As Senior Engineering Manager, AI Platform, you will lead the engineering team building the connected intelligence system behind Sequencing’s current and future AI-powered products. Reporting to the Senior Director, AI & Emerging Technologies, you will turn clear product direction into focused engineering execution across data, retrieval, memory, integrations, agent orchestration, evaluation, observability, and reliability.

## What they're looking for

- You have 8+ years of software engineering experience, including 3+ years managing or leading high-performing engineering teams
- You have at least 2 years of experience building production LLM, generative-AI, or agentic products
- You have designed or shipped systems involving tool use, orchestration, memory, retrieval, prompts or skills, evaluation loops, and human review
- You are technically credible across distributed systems, data pipelines, APIs, cloud infrastructure, and production reliability
- You can engage deeply on system design and failure modes while empowering senior engineers to own architecture and implementation
- You have built strong engineering cultures grounded in ownership, growth mindset, direct feedback, and continuous improvement

Tags: Engineering

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/sequencing-senior-engineering-manager-ai-platform/