# Research Scientist, AI at Substrate

- Company: Substrate
- What the company does: Substrate is building America. Backed by General Catalyst.
- Company website: https://substrate.com/
- Type: Startups (AI role)
- Level: Mid level
- Location: San Francisco
- Work setup: On-site
- Pay: $150K to $275K base salary per year (USD)
- Posted: 2025-10-28
- Apply by: 2026-10-08
- Apply: https://jobs.ashbyhq.com/substrate/6e8771ea-e475-493c-921c-1448520bddd5
- Page: https://www.1752.vc/careers/jobs/substrate-research-scientist-ai/

## About the role

Integrate machine learning techniques to accelerate scientific simulations, modeling, and computational workflows Develop AI-augmented tools for materials science, device physics, or accelerator physics applications

## What they're looking for

- 5+ years professional or academic research experience in physical sciences, engineering, or related field
- 2-3+ years hands-on experience applying machine learning to scientific or technical problems
- Strong programming skills in Python and ML frameworks (PyTorch, TensorFlow, JAX, or similar)
- Deep understanding of scientific computing, numerical methods, and computational modeling
- Proven ability to translate scientific problems into machine learning approaches
- Experience building tools, infrastructure, or capabilities used by technical teams

Tags: Scientific