# Senior Machine Learning Scientist at Tahoe Therapeutics

- Company: Tahoe Therapeutics
- What the company does: Reasoning models can now generate hypotheses in seconds. Verifying them requires biological ground truth. Tahoe is building that ground truth. Backed by General Catalyst and Amplify.
- Company website: https://www.tahoebio.ai/
- Type: Startups (AI role)
- Level: Senior
- Location: South San Francisco
- Work setup: On-site
- Pay: $200K to $275K base salary per year (USD)
- Posted: 2025-11-17
- Apply by: 2026-10-08
- Apply: https://jobs.lever.co/tahoebio-ai/8fe3e406-050f-498c-8f75-3cb780dec092
- Page: https://www.1752.vc/careers/jobs/tahoe-therapeutics-senior-machine-learning-scientist/

## About the role

With Tahoe-100M, we solved one of the fundamental bottlenecks in building a virtual model of the cell: generating massive, perturbation-rich, single-cell datasets that capture real biological causality. With Tahoe-x1 , we removed the second bottleneck: creating a modern platform for rapid iteration on model architectures and designs in a cost-efficient manner and at scale.

## What they're looking for

- PhD or equivalent practical experience in a technical field
- A proven track record of developing and applying deep learning methods, including experience with modern architectures such as transformers, state-space models, graph neural networks or diffusion-based generative models
- Proficiency with modern ML frameworks (e.g., PyTorch, JAX, or TensorFlow) and core scientific computing libraries (e.g., NumPy, SciPy, Pandas)
- A genuine enthusiasm for applying cutting-edge ML research to real-world biological problems and a bias towards action

Tags: Machine Learning