# Senior Research Associate, Oligonucleotide Chemistry at Tessera Therapeutics

- Company: Tessera Therapeutics
- What the company does: Tessera Therapeutics is an early-stage life sciences company pioneering Gene Writing™, a new biotechnology designed to offer scientists and doctors the…. Backed by SoftBank VF.
- Company website: https://tesseratherapeutics.com/
- Type: Startups
- Level: Senior
- Location: Somerville, Massachusetts, United States
- Work setup: On-site
- Pay: $90K to $108K base salary per year (USD)
- Posted: 2026-09-16
- Apply by: 2026-10-31
- Apply: https://job-boards.greenhouse.io/tesseratherapeutics/jobs/5240104007
- Page: https://www.1752.vc/careers/jobs/tessera-therapeutics-senior-research-associate-oligonucleotide-chemistry/

## About the role

You are a skilled and self-motivated individual who can optimize and implement processes for synthesizing and purifying complex oligonucleotides. You can operate in a fast-paced environment, troubleshoot instruments, and document operations independently and as part of a team. You will have the opportunity to organize and present results within the group and interface with other teams, so strong communication skills are critical. You enjoy overcoming challenges in collaboration with colleagues.

## What they're looking for

- BS/MS in Chemistry, Biochemistry, Chemical Engineering, or related field with 5+ years (BS) or 3+ years (MS) of relevant industry experience
- Experience with upstream and downstream processing of oligonucleotides
- Must have experience with Mermade192 and Mermade12 synthesizers
- Experience with Äkta100 oligonucleotide synthesizer is a plus
- Experience with HPLC purification and analytics of guide RNA preferred
- Experience with enzymatic ligation techniques is a plus

Tags: Chemistry