# Principal Information System Engineer at Treeline Biosciences

- Company: Treeline Biosciences
- What the company does: Backed by GV.
- Company website: https://treeline.bio
- Type: Startups
- Level: Principal and up
- Location: Watertown, Massachusetts, United States
- Work setup: On-site
- Pay: $180K to $197K base salary per year (USD)
- Posted: 2026-08-27
- Apply by: 2026-10-11
- Apply: https://job-boards.greenhouse.io/treelinebiosciences/jobs/6166610004
- Page: https://www.1752.vc/careers/jobs/treeline-biosciences-principal-information-system-engineer/

## About the role

We are seeking an experienced and customer-focused Principal Information System Engineer to join our IT team. The ideal candidate will have strong experience managing modern workplace technologies and troubleshooting complex technical issues. This role reports to our Director, IT Operations and will work closely with both our in-house engineers and Managed Service Providers (MSPs) supporting Treeliners from every department across multiple countries.

## What they're looking for

- Bachelor's degree in Information Technology, Computer Science, or related field, or equivalent work experience
- 8-10+ years of experience in systems administration, endpoint management, identity management, or IT operations
- A broad range of overall IT experience, including Windows, Mac, Databases, Storage, Security, Networking and public clouds
- Strong hands-on experience with the following or similar:
- Microsoft 365 Administration
- Microsoft Intune

Tags: IT