# Principal Engineer, Pharma CMC Manufacturing & Tech Transfer at Varda

- Company: Varda
- What the company does: Expanding the economic bounds of humankind with the world's first orbital manufacturing & reentry platform. Backed by General Catalyst, Khosla and Founders Fund.
- Company website: https://varda.com/
- Type: Startups
- Level: Principal and up
- Location: El Segundo, California, United States
- Work setup: On-site
- Pay: $187K to $239K base salary per year (USD)
- Posted: 2026-10-22
- Apply by: 2026-12-06
- Apply: https://job-boards.greenhouse.io/vardaspace/jobs/8042347003?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/varda-principal-engineer-pharma-cmc-manufacturing-and-tech-transfer/

## About the role

Our CMC team is looking for a highly motivated and experienced Principal Engineer, Pharma CMC Manufacturing & Tech Transfer to lead process transfer, CDMO qualification, pilot scale manufacturing, and GMP manufacturing oversight for Varda's crystallization and drug product pipeline. Reporting to the VP, CMC, this role owns the path from a lab-characterized process to a validated, transferable manufacturing package executed reliably across a network of external partners. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Own technology transfer execution: translate R&D developed processes into robust, CDMO-ready transfer packages
- Lead pilot plant production of material to support nonclinical development
- Lead selection, qualification, and ongoing management of CDMO partners across the manufacturing network (Crystallization, Fill-Finish, and DS Partner), including RFPs, technical due diligence, and capability assessments
- Lead tech transfer of drug product fill-finish processes for the crystalline suspension, partnering with R&D on process- and product-specific technology transfer coordination
- Negotiate and manage Manufacturing Services Agreements with CDMO partners, defining scope, key terms, and deliverables, in partnership with Legal and Quality
- Establish the CDMO oversight model, including defined chain of custody across CDMO handoffs

Tags: Pharma

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/varda-principal-engineer-pharma-cmc-manufacturing-and-tech-transfer/