# Senior / Principal Scientist Analytical Method Development Lead at Vaxess Technologies

- Company: Vaxess Technologies
- What the company does: Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1. Terrestrial. Backed by Ulu Ventures.
- Company website: https://vaxess.com
- Type: Startups
- Level: Principal and up
- Location: Woburn, MA
- Work setup: On-site
- Pay: $125K to $180K base salary per year (USD)
- Posted: 2026-08-28
- Apply by: 2026-10-19
- Apply: https://jobs.ashbyhq.com/terrestrialbio/1fce9d13-cc3a-41f3-9639-39c0af723aa8?utm_source=1752vc&utm_medium=careers
- Page: https://www.1752.vc/careers/jobs/vaxess-technologies-senior-principal-scientist-analytical-method-development-lea/

## About the role

Lead analytical method development for release and characterization assays including RP-HPLC/UPLC purity, content, SEC, and impurity characterization by LC-MS. Define and execute the analytical method validation strategy per ICH Q2(R2) and Q14. Found on 1752vc Careers, the job board for startup and VC roles.

## What they're looking for

- Ph.D. in Analytical Chemistry, Biochemistry, or related field with 6+ years relevant experience, OR M.S. with 8+ years in pharmaceutical/biotech analytical method development
- Deep expertise in HPLC/UPLC method development for peptides or biologics
- Hands-on experience with LC-MS for impurity characterization and structural analysis
- Demonstrated experience leading method validation under ICH Q2(R2)/Q14
- Experience developing analytical control strategies and specifications for clinical-stage products
- Strong knowledge of ICH Q6A, Q3A/B/C/D, and FDA/EMA CMC expectations

Tags: Analytical Sciences

Source: 1752vc Careers, https://www.1752.vc/careers/jobs/vaxess-technologies-senior-principal-scientist-analytical-method-development-lea/